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International study discovers three potential new targets for treating epilepsy

Professor David Henshall
Pictured is Professor David Henshall, Professor of Molecular Physiology and Neuroscience at RCSI and Director of FutureNeuro, who co-authored a paper that has found a pattern of molecules that appear in the blood before a seizure happens, which may lead to the development of an early warning system for those with epilepsy. Photograph: Patrick Bolger

A major international study has uncovered three molecules that have the potential to be developed into new drugs to treat epilepsy. The findings are an important step towards discovering new drugs for people with epilepsy whose seizures cannot be controlled with current treatments.

The study was led by researchers at FutureNeuro, the SFI Research Centre for Chronic and Rare Neurological Diseases and RCSI University of Medicine and Health Sciences. It is the result of seven years of research, involving contributions from 35 scientists, based in eight different European countries, across the fields of neuroscience, genetics, computer science and synthetic chemistry. The research is published in the current issue of Proceedings of the National Academy of Sciences (PNAS) USA.

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