The All-Ireland Liquid Biopsy Consortium (CLuB; www.clubcancer.ie) is a collaborative program focused on advancing liquid biopsy technologies for cancer diagnosis and treatment. It unites researchers, clinicians, patients and institutions across both Northern Ireland and the Republic of Ireland. The consortium aims to develop minimally invasive, cost-effective, and reliable liquid biopsy methods that could complement or, in some cases, replace traditional tissue biopsies. These blood tests seek to enable earlier and more precise diagnoses, support personalised treatment strategies, and enhance patient outcomes. By combining expertise across the island, the consortium accelerates innovation in the field of liquid biopsy.
CLuB is led by Prof Lorraine O’Driscoll in Trinity College Dublin and the Northern Ireland lead is Prof Paul Mullan in Queens University Belfast (QUB). It is funded by the Higher Education Authority under the North South Research Programme, emerging hub of excellence. The premise of CLuB was to amalgamate the fragmented research that was happening across the country so that the information is maximised for liquid biopsies from patients. This information would then be processed by data scientists in the University of Galway under the direction of Dr Pilib Ó Broin to develop better algorithms for diagnosis and treatment.
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