Written by Professor Carel Le Roux, MBChB, FRCP, FRCPath, PhD, Diabetes Complications Research Centre, UCD and Dr Sarah Cooney, MBChB, Academic Intern, Beaumont Hospital
Type 2 diabetes is a heterogeneous syndrome caused by abnormalities in carbohydrate and fat metabolism. The causes of type 2 diabetes are multifactorial and include both genetic and environmental elements that affect beta cell function and tissue sensitivity. 1 However, despite this expansive description, in clinical practice currently type 2 diabetes tends to be oversimplified with a one size fits all approach. Recent developments have changed our understanding of the diversity within type 2 diabetes, which may hold the key to better treatment.
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