Clinical Features

Type 2 Diabetes: A Cluster of Diseases

A Cluster of Diseases: Type 2 diabetes is a heterogeneous syndrome caused by abnormalities in carbohydrate and fat metabolism.

Type 2 Diabetes

Written by Professor Carel Le Roux, MBChB, FRCP, FRCPath, PhD, Diabetes Complications Research Centre, UCD and Dr Sarah Cooney, MBChB, Academic Intern, Beaumont Hospital

Type 2 diabetes is a heterogeneous syndrome caused by abnormalities in carbohydrate and fat metabolism. The causes of type 2 diabetes are multifactorial and include both genetic and environmental elements that affect beta cell function and tissue sensitivity. 1 However, despite this expansive description, in clinical practice currently type 2 diabetes tends to be oversimplified with a one size fits all approach. Recent developments have changed our understanding of the diversity within type 2 diabetes, which may hold the key to better treatment.

For verified healthcare professionals

Log in or register for free to read this article. HPN is for healthcare professionals, so new accounts are verified by our team.

Register for free Log in

Join the conversation

Comments are open to registered members. Log in or register to share your thoughts on this article.

Log in to comment Register for free