Abstract: Malignant pleural effusion (MPE) is a common clinical entity affecting 40,000 people per year in the UK. Malignant pleural effusion can occur with a primary pleural malignancy, typically mesothelioma or more commonly as a metastatic manifestation of a non pleural primary malignancy. In Ireland mesothelioma is an infrequent diagnosis and therefore the majority of cases of MPE represent advanced Stage IV malignant disease. 1
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