Introduction: Psoriasis is a chronic multisystem autoimmune disease with cutaneous involvement. It is characterised by the rapid growth of skin cells, leading to the formation of thick, red, and scaly plaques, although other presentations can occur.
Approximately 73,000 people have psoriasis in Ireland. Individuals with moderate to severe psoriasis often experience significant physical and psychological co-morbidities. Most patients with psoriasis can be treated in primary care or in the outpatient setting. However, life-threatening presentations such as erythrodermic psoriasis or pustular psoriasis can require intensive inpatient management. While severe psoriasis should be managed by consultant dermatologists with access to advanced therapeutics, this article explores the various treatment options available for moderate to severe psoriasis, highlighting the importance of personalised and multimodal approaches.
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