High-Risk Multiple Myeloma (MM)

Introduction: Multiple myeloma (MM) is a haematological malignancy characterised by the clonal expansion of malignant plasma cells in the bone marrow.

MM manifests clinically as hypercalcaemia, renal failure, anaemia and bone lesions (known as CRAB features), with a median age of diagnosis of 71 in Ireland.1 MM affects around 384 people in Ireland each year1 and despite advancements in treatments remains incurable in 2024, as patients eventually relapse.